

Obesity is associated with PCOS and can worsen complications of the disorder. Cancer of the uterine lining (endometrial cancer).Depression, anxiety and eating disorders.Metabolic syndrome - a cluster of conditions including high blood pressure, high blood sugar, and abnormal cholesterol or triglyceride levels that significantly increase your risk of cardiovascular disease.Nonalcoholic steatohepatitis - a severe liver inflammation caused by fat accumulation in the liver.Gestational diabetes or pregnancy-induced high blood pressure.The ovaries produce abnormally high levels of androgen, resulting in hirsutism and acne. Research suggests that certain genes might be linked to PCOS. Research has shown that women with PCOS have a type of low-grade inflammation that stimulates polycystic ovaries to produce androgens, which can lead to heart and blood vessel problems. This term is used to describe white blood cells' production of substances to fight infection. Excess insulin might increase androgen production, causing difficulty with ovulation. If your cells become resistant to the action of insulin, then your blood sugar levels can rise and your body might produce more insulin. Insulin is the hormone produced in the pancreas that allows cells to use sugar, your body's primary energy supply. Request an Appointment at Mayo Clinic Causes See your doctor if you have concerns about your menstrual periods, if you're experiencing infertility or if you have signs of excess androgen such as worsening hirsutism, acne and male-pattern baldness. PCOS signs and symptoms are typically more severe if you're obese.


As a result, the ovaries might fail to function regularly. Your ovaries might be enlarged and contain follicles that surround the eggs. Elevated levels of male hormones may result in physical signs, such as excess facial and body hair (hirsutism), and occasionally severe acne and male-pattern baldness. For example, you might have fewer than nine periods a year, more than 35 days between periods and abnormally heavy periods. Infrequent, irregular or prolonged menstrual cycles are the most common sign of PCOS. A diagnosis of PCOS is made when you experience at least two of these signs: Sometimes PCOS develops later, for example, in response to substantial weight gain. Signs and symptoms of PCOS often develop around the time of the first menstrual period during puberty.
